Skp2 (GWB-6B3D11)

GWB-6B3D11

10-786-259097

0.01 mg
$394.20

Description

Amino Sequenceaa 221-425 Activity: Not known

Characterization: On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 49kDa (including GST). SKP2 is a substrate recognition component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. SKP2 specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. This gene is established as a protooncogene causally involved in the pathogenesis of lymphomas (referenced from swissprot).

Additional Information

Name Skp2 (GWB-6B3D11)
Related Product Names RECOMBINANT HUMAN SKP2 PROTEIN Skp2
Source Recombinant human skp2 protein encoding aa 221-425 expressed in
Application ELISA, IA, WB
Format 100ul purified human skp2 Protein At 100ug/ ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA, 20% Glycerol without BSA and Sodium Azide.
Datasheets/Manuals Printable datasheet for GWB-6B3D11
Storage Store vial at -20C to -80C. When stored at the recommended temperature, this protein is stable for 12 months.
Intended Use Research Use Only