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c-Myc Peptide (GWB-4EFA81)



5 mg
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Sequence (One Letter Code): EQKLISEEDL

Sequence: {GLU} {GLN} {LYS} {LEU} {ILE} {SER} {GLU} {GLU} {ASP} {LEU}

Formula: C51H86N12O21

Solubility: Soluble in PBS. pH 7.0. The optimal working dilution should be determined for each specific assay condition.

c-Myc Peptide is a useful for displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc Peptide demonstrates binding is specific. c-Myc Peptide participates in regulation of growth-related gene transcription.

The aa squence of c-Myc peptide corresponds to aa 410-419 of the C-terminal of human c-Myc. This peptide is for laboratory research use only.

Function: Participates in the regulation of gene transcription. Binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5\'-CAC[GA]TG-3\'. Seems to activate the transcription of growth-related genes (By similarity).

Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. [1] Bernstein,P.L., Herrick,D.J., Prokipcak,R.D. and Ross,J., et al.
Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant
[2] Bernstein P.L., Herrick D.J., Prokipcak R.D., Ross J.
Control of c-myc mRNA half-live in vitro by a protein capable of binding to a coding region stability determinant.

Additional Information

Name c-Myc Peptide (GWB-4EFA81)
Availability In Stock
Related Product Names c-Myc Peptidec-myc
Swissprot ID Q6LBK7
NCBI Acc Number CAA46984.1
Purity > 95%
GI Number 396512
Stability 6-12 months at -20 degree C.
Sequence Length 60
Storage 4 degree C for short term (weeks) and -20 degree C for long term.
Datasheets/Manuals Printable datasheet for GWB-4EFA81
Intended Use Research Use Only