CNTF Protein (GWB-56D467)

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GWB-56D467

10-663-46549

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Name CNTF Protein (GWB-56D467)
Availability In Stock
Related Product Names CNTF, His, Ciliary Neurotrophic Factor Recombinant, His Tag, HCNTF, CNTF, Ciliary Neurotrophic Factor Recombinant Human Ciliary Neurotrophic Factor, His TagCNTF His
Description of Target Recombinant Human Ciliary Neurotrophic Factor, His Tag
Gene Symbol CNTF His
Gene id 1270
Alias Symbols HCNTF, CNTF, Ciliary Neurotrophic Factor, CNTF Human, His, Ciliary Neurotrophic Factor Human Recombinant, His Tag
Swissprot ID P26441
Protein Name Ciliary neurotrophic factor
Protein Accession Num NP_000605.1
Host E. Coli
Peptide Sequence MGSSHHHHHH SSGLVPRGSH MAFTEHSPLT PHRRDLCSRS IWLARKIRSDLTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM.
Product Format CNTF His tag protein solution contains 20mM Tris buffer pH-8 and 1mM DTT. Physical appearance: Sterile Filtered colorless clear solution at a concentration of 1mg/ml.
Purity Greater than 95.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Format CNTF His tag protein solution contains 20mM Tris buffer pH-8 and 1mM DTT.
Reconstitution and Storage CNTF his tag fusion protein although stable 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze-thaw cycles.
Storage CNTF his tag fusion protein although stable 4C for 1 week, should be stored desiccated below -18 C. Please prevent freeze-thaw cycles.
Datasheets/Manuals Printable datasheet for GWB-56D467
Intended Use Research Use Only
:: Product Introduction: CNTF is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor.CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
Product Description: Ciliary Neurotrophic Factor Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 220 amino acids and having a molecular mass of 25 kDa. The CNTF protein is fused to His Tag at N-terminus.The CNTF is purified by proprietary chromatographic techniques.