Description
Similarity: Contains 9 LDL-receptor class B repeats.
Function: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
Function: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
Additional Information
| Name | EGF Protein (GWB-AB1AFA) |
|---|---|
| Related Product Names | MOUSE EGF EGFEGF |
| Gene Symbol | Egf |
| Gene id | 13645 |
| Alias Symbols | AI790464, Egf |
| Swissprot ID | P01132 |
| Protein Name | Pro-epidermal growth factor |
| Description of Target | MOUSE EGF |
| Protein Accession Num | NP_034243.2 |
| Homology | Mouse |
| NCBI Acc Number | NP_001954.2 |
| Product Format | Purified natural EGF - lyophilised |
| Specificity | EGF exhibits growth stimulating properties on various epidermal and epithelial tissues, both in vivo and in vitro. |
| Purity | >95% by SDS PAGE_x000D_ |
| Application | FA |
| Format | Purified |
| Stability | 18 months from date of despatch. |
| Species Reactivity | Mouse |
| Reconstitution and Storage | Reconstitution: Reconstitute with 1.0ml phosphate buffered saline (PBS). Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Aviva Systems Biology recommend that the vial is gently mixed after reco |
| Reactivity | Mouse |
| Datasheets/Manuals | Printable datasheet for GWB-AB1AFA |
| Storage | Prior to reconstitution store at +4 degree C. Following reconstitution store at -20 degree C. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the pr |
| Lead Time | Domestic: within 2-3 weeks delivery | International: 2-3 weeks |
| Intended Use | Research Use Only |
| Key Reference | 1. Savage, C. R. Jr. and Cohen, S. (1972) Epidermal growth factor and a new derivative. Rapid isolation procedures and biological and chemical characterization. J Biol Chem. 247:7609-7611 |
| Additional Information | Approx Protein Conc: Total protein concentration 1.0mg/ml after reconstitution |
| :: | Label Protein Molar Ratio: Purified from the submaxillary glands of male mice, using a modification of the method of Savage and Cohen(1). Preservative: None present |