GADD153

We have 10 GADD153

    10 Item(s)

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    1. $311.40
      GenWay ID: GWB-6BAD20
      Legacy ID: 36-614-469303
      Item Type: Default Category, Proteins, Over-expression Lysate, GADD153.
      Application(s): WB

    2. Varies by Size
      GenWay ID: GWB-AB78E7
      Legacy ID: 10-663-46676
      Item Type: Default Category, Proteins, Recombinant Proteins, GADD153.

    3. Varies by Size
      GenWay ID: GWB-AEAAA3
      Legacy ID: 10-002-38156
      Item Type: Default Category, Proteins, Recombinant Proteins, GADD153.
      Application(s): SDS

    4. Varies by Size
      GenWay ID: GWB-P0191I
      Reactivity: Human
      Item Type: Default Category, Proteins, Recombinant Proteins, GADD153.

    5. $426.60
      GenWay ID: GWB-711FF7
      Legacy ID: 18-272-195087
      Reactivity: Cross-reacts with Human and Rat. Expected to cross-react with Mouse (88% identity with immunogen) and Xenopus laevis (85% identity with immunogen) due to sequence homology. Not yet tested in other species.
      Item Type: Default Category, Polyclonal, Antibodies, GADD153.
      Application(s): Isotype: IgG

      Immunogen: Synthetic peptide: KEATRRALIDRMVNLHQA conjugated to KLH, corresponding to amino acids 153-169 of Human DDIT3 (with added N-terminal K).

      Antigen Species: Human Positive Control: Whole extract of growth arrested rat PC 12 pheochromocytoma cells

      Target: DDIT3

      Localization: Nuclear

      Concentration: 1.2 mg/ml Storage Buffer: Preservative: 15mM Sodium Azide; Constituents: 1% BSA, 0.01M PBS. pH 7.4

      Application Note: WB: Use at a dilution of 1/250. Detects a band of approximately 29 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

      Cellular Localization: Nuclear DDIT3 is a basic region leucine zipper transcription factor, devoid of DNA binding site. It is capable of heterodimerizing with members of the CCAAT/ enhancer binding protein (C/EBP) family of transcription factors. It is both an activating and a repressing factor that is markedly induced in response to many signals such as growth arrest, DNA damage, calcium ionophore, nutrient deprivation, hypoxia, hyperoxia, hyperosmosis, and endoplasmic reticulum stress.

      Function: Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA.

      Subunit: Heterodimer.

      Subcellular Location: Nucleus.

      Disease: A chromosomal aberration involving DDIT3 is found in a form of malignant myxoid liposarcoma [MIM:126337]. Translocation t(12;16)(q13;p11) with FUS.

      Similarity: Belongs to the bZIP family.

    6. $477.90
      GenWay ID: GWB-D02516
      Legacy ID: 18-464-435162
      Reactivity: Human
      Item Type: Default Category, Polyclonal, Antibodies, GADD153.

    7. $394.25
      GenWay ID: GWB-E3C4D2
      Legacy ID: 20-272-190514
      Reactivity: Human, Mouse
      Item Type: Default Category, Antibodies, Monoclonal, GADD153.
      Application(s): ICC/IF, IP, WB

    8. Varies by Size
      GenWay ID: GWB-ASB388
      Reactivity: Human
      Item Type: Polyclonal, Antibodies, Th, Protein, GADD153.
      Application(s): WB IHC IF ELISA

    9. Varies by Size
      GenWay ID: GWB-ASC407
      Reactivity: Human
      Item Type: Polyclonal, Antibodies, Th, Protein, GADD153.
      Application(s): WB IHC IF ELISA

    10. Varies by Size
      GenWay ID: GWB-ASD076
      Reactivity: Human
      Item Type: Polyclonal, Antibodies, Th, Protein, GADD153.
      Application(s): WB IHC IF ELISA

    10 Item(s)

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