Human TGF beta 1 ELISA Kit (GWB-ZZD028)


96 wells
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Transforming growth factor-beta1(TGF-beta1) is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGF-beta and essentially all of them have specific receptors for this peptide. TGF-beta regulates the actions of many other peptide growth factors and determines a positive or negative direction of their effects.TGFbeta1 is known for its potent and diverse biological effects, including immune regulation, and cell growth and differentiation.TGFbeta1 is also an important mediator of bone remodeling.TGFbeta1, a potent keratinocyte growth inhibitor, has been shown to be overexpressed in keratinocytes in certain inflammatory skin diseases and has been thought to counteract the effects of other growth factors at the site of inflammation.TGF-beta1, a multifunctional cytokine with fibrogenic properties, has been implicated in the pathogenesis of the vascular and target organ complications of hypertension. TGF-beta1 may also regulate blood pressure via stimulation of endothelin-1 and/or renin secretion. TGFbeta1 is secreted as a latent form, which consists of its mature form and a latency-associated peptide(beta1-LAP) in either the presence or the absence of additional latent TGF-beta1-binding protein. The standard product used in this kit is recombinant TGFbeta1 with the molecular mass of 25KDa.

Additional Information

Name Human TGF beta 1 ELISA Kit (GWB-ZZD028)
Related Product Names Camurati-Engelmann disease| CED| DPD1| LAP| Latency-associated peptide| TGF beta 1 protein| TGF-beta-1| TGFB| tgfb1| TGFB1_HUMAN| TGFbeta| Transforming growth factor beta 1
Short Description Sandwich ELISA kit of Quantitative Detection for Human TGF beta 1
Sample Type This kit is used for quantitative detection of activated human TGFbeta 1 in cell culture supernates, serum, plasma(EDTA) and urine.
Swissprot ID P01137
Immunogen CHO, A279-S390
Standard Range 15.6pg/ml-1000pg/ml. Test has a sensitivity of < 1 pg/ml
Specimen/Volumes Refer to Manual
Concentration Lot Specific
Application ELISA
GI Number 7040
Stability Four months at 4C and eight months at -20C.
Reactivity Reactive to Human. There is cross-reactivates with TGF beta 2, TGF beta 3, TGF beta 5<1%.
Kit Size 1x96 well plate
Datasheets/Manuals Printable datasheet for GWB-ZZD028
Storage Store at 4C for 6 months, at -20C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
Intended Use Research Use Only