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Cyclophilin A Protein (GWB-14EF58)

GWB-14EF58

10-663-45904

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Description

Similarity: Contains 1 PPIase cyclophilin-type domain.

Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Additional Information

Name Cyclophilin A Protein (GWB-14EF58)
Related Product Names Peptidylprolyl isomerase A, CYPA, CYPH, MGC12404, MGC23397, MGC117158, PPIase A, Rotamase A, PPIA, Peptidyl-prolyl cis-trans isomerase A, EC 5.2.1.8, Cyclophilin A, Cyclosporin A-binding protein.; PPIase A; Rotamase A; EC 5.2.1.8; Cyclophilin A; Cyclospor
Drywet Surcharge 0
Gene Symbol Cyclophilin A
Gene id 5478
Alias Symbols Peptidylprolyl isomerase A, CYPA, CYPH, MGC12404, MGC23397, MGC117158, PPIase A, Rotamase A, PPIA, Peptidyl-prolyl cis-trans isomerase A, EC 5.2.1.8, Cyclophilin A, Cyclosporin A-binding protein, Cyclophilin A Human, Cyclophilin-A Human Reco
Protein Name Peptidyl-prolyl cis-trans isomerase A
Description of Target PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. Cyclophilin-A is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. Cyclophil
Swissprot ID P62937
Protein Accession Num NP_066953.1
Peptide Sequence MGSSHHHHHH SSGLVPRGSH MVNPTVFFDI AVDGEPLGRV SFELFADKVP KTAENFRALSTGEKGFGYKG SCFHRIIPGF MCQGGDFTRH NGTGGKSIYG EKFEDENFIL KHTGPGILSMANAGPNTNGS QFFICTAKTE WLDGKHVVFG KVKEGMNIVE AMERFGSRNG KTSKKITIADCGQLE.
NCBI Acc Number NP_066953.1
Product Format 1 mg/ml solution containing 20mM Tris 8.0, 20mM NaCl, 0.5mM DTT and 10% glycerol. Physical appearance: Sterile filtered colorless solution.
Datasheets / Downloads GWB-14EF58 Datasheet
Swiss Prot Number P62937
Biological Activity Specific activity is > 270 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 25C in Tris-Hcl pH8.0 using chymotrypsin.
Purity Greater than 95.0% as determined by SDS-PAGE.
Source E. coli
Format 1 mg/ml solution containing 20mM Tris 8.0, 20mM NaCl, 0.5mM DTT and 10% glycerol.
Stability PPIase-A Human Recombinant although stable at 4C for 1 week, should be stored desiccated below -18 C.
Please prevent freeze thaw cycles.
Reconstitution and Storage Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Intended Use Research Use Only