HCV NS3 Genotype-5 Protein (GWB-108A7F)

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GWB-108A7F

10-663-45434

100ug
$179.00
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Description

Similarity: Contains 1 RdRp catalytic domain.

Function: NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication (By similarity).

Additional Information

Name HCV NS3 Genotype-5 Protein (GWB-108A7F)
Related Product Names Hepatitis C Virus NS3 Genotype-5, 1192-1459 Recombinant; N/A HCV NS3 Genotype-5
Gene Symbol HCV NS3 Genotype-5
Alias Symbols HCV NS3 Genotype-5, Hepatitis C Virus NS3 Genotype-5, (1192-1459 a.a.) Recombinant
Swissprot ID O39928
Description of Target Recombinant Hepatitis C Virus NS3 Genotype-5 (1192-1459)
Application Info HCV NS3 Genotype-5 antigen in ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
Product Format 1.5M urea, 25mM Tris-HCl pH-8, 0.2% Triton-X & 50% Glycerol.
Specificity Immunoreactive with sera of HCV-infected individuals.
Purity HCV NS3 Genotype-5 protein is >95% pure as determined by 10% PAGE (coomassie staining).
Purification: HCV NS3 Genotype-5 protein was purified by proprietary chromatographic technique.
Format 1.5M urea, 25mM Tris-HCl pH-8, 0.2% Triton-X & 50% Glycerol.
Stability Five years frozen. One month in solution at room temperature.
Reconstitution and Storage HCV NS3 Genotype-5 protein is shipped at ambient temperature. Upon arrival, Store at -20C.
Stability: Five years frozen. One month in solution at room temperature.
Datasheets/Manuals Printable datasheet for GWB-108A7F
Storage Protein is shipped at ambient temperature.
Upon arrival, Store at -20 C.
Lead Time Domestic: within 1-2 weeks delivery | International: 1-2 weeks
Intended Use Research Use Only
:: Product Introduction: HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Product Description: The E.coli derived recombinant protein contains the HCV NS3 immunodominant regions, amino acids 1192-1459.