Human Apolipoprotein AI (GWB-108328)



500 ug
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Additional Information

Name Human Apolipoprotein AI (GWB-108328)
Gene Symbol APOA1
Gene id 335
Alias Symbols APOA1, Apo-AI, Apolipoprotein A1
Swissprot ID P02647
Description of Target This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein.
NCBI Acc Number NP_000030.1
Product Format Liquid 10 mM Ammonium Bicarbonate (NH4HCO3), pH 7.4
Purification Column chromatography
Concentration 2.21 mg/ml (OD280nm, E1% = 12.2)
Purity > 95% pure (SDS-PAGE)
Source High Density Lipoprotein (HDL) from pooled human plasma
Application Specific methodologies have not been tested using this product.
Reconstitution and Storage Upon receipt, store at -70C. Keep concentration >1 mg/ml as precipitation may occur below 1 mg/ml. Avoid multiple freeze/thaw cycles.
Datasheets/Manuals Printable datasheet for GWB-108328
Additional Information Important Note: Centrifuge before opening to ensure complete recovery of vial contents.