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Mouse Seroblock FcR Antibody

GWB-Q00316

0.5 mg
$605.00
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Description

Short Description: MOUSE SEROBLOCK FcR

Additional Information

Name Mouse Seroblock FcR Antibody
Related Product Names MOUSE SEROBLOCK FcR Reagent, Flow Cytometry, MOUSE SEROBLOCK FcR
Drywet Surcharge 0
Description of Target MOUSE SEROBLOCK FcR
Species Reactivity Mouse
Clone FCR4G8
Isotype IgG2b
Immunogen PU5 1.8 IOE7 Balb/c mouse cell line
Homology Mouse
Product Format Purified IgG - liquid
Datasheets / Downloads GWB-Q00316 Datasheet
Specificity This product is a rat antibody that recognises mouse CD16 and CD32, cell surface proteins also known as FcRgammaIII and FcRgammaII, respectively.
The function of these proteins is to bind IgG molecules via their Fc regions as part of the adaptive immune response. CD16 and/or CD32 are expressed by a wide variety of cells, including monocytes, macrophages, B lymphocytes, granulocytes, NK cells, dendritic cells and some activated T lymphocytes.
The expression of CD16/CD32 antigens can lead to non-specific binding of test monoclonal antibodies in staining procedures, resulting in œhigh background  staining on a wide range of cells. This non-specific binding may be blocked by pre-incubation of target cells with This product , resulting in clearer staining.
For direct analysis of CD16/32 expression this antibody is also available conjugated directly to FITC (MCA2305F), AlexaFluor488 (MCA2305A488), AlexaFluor647 (MCA2305A647), Biotin (MCA2305B) and RPE (MCA2305PE).
Concentration 1.0mg/ml
Applications F
Clonality IgG2b
Format Solution: Phosphate buffered saline, Stabalizer: 0.09%, Sodium Azide , Form: Purified IgG - liquid
Stability 18 months from date of despatch.
Reconstitution and Storage Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Reactivity Mouse
Storage Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate
Intended Use Research Use Only
Key Reference 1. Ivanovska, N.D et al . (2008) Properdin Deficiency in Murine Models of Nonseptic Shock. The Journal of Immunology. 180: 6962-6969.
2. Chen, H-F et al . (2009) A reduced oxygen tension (5%) is not beneficial for maintaining human embryonic stem cells in the undifferentiated state with short splitting intervals. Human Reproduction. 24: 71-80.
Additional Information Approx Protein Conc: IgG concentration 1.0mg/ml
Buffer solution: Phosphate buffered saline, pH7.4
:: Label Protein Molar Ratio: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Preservative: 0.09% - Sodium Azide (NaN3)