The status of nativity of protein antigens when used as immunogens and their reactivities with the antibodies produced are the most critical factors of a quality antigen.
Antibodies to native proteins react best with native proteins and antibodies to denatured proteins react best with denatured proteins. If elicited antibodies are to be used on membrane blots (proteins subjected to denaturing conditions) then antibodies should be made against denatured proteins.
On the other hand, if antibodies are to be used to react with a native protein or block a protein active site, then antibodies should be made against the native protein.
GenWay prepares native antigens by using conventional methods in protein isolation and purification such as protein precipitation, partitioning, fractionation, liquid chromatography, affinity separation, etc.
Search GenWay's Native Protein Catalog of products.
For other types of antigens, please visit the pages: