Vitamin D Bind.Prot(GC-Glob.)

GWB-5BEEF2
11-511-248771
1 mg
$174
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Description

Specificity: Vitamin D Binding Protein (Gc-Globulin)

Preservative: None Inactivation: Not applicable.

Buffer: Lyophilized from 20mM Sodium Phosphate, pH 7.4 containing 150mM Sodium chloride

Applications Notes : Specific methodologies have not been tested using this product. Concentration: Concentration is lot specific

Preservative: None

Description: Molecular weight 52kDa (SDS-PAGE, reducing conditions) Vitamin D Bind.Prot (GC-Glob.). Purified Vitamin D Binding Protein (GC Globulin). Molecular weight 52kDa (SDS-PAGE, reducing conditions)

Function: Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.

Subcellular Location: Secreted.

Polymorphism: Over 80 variants of human DBP have been identified. The three most common alleles are called GC*1F, GC*1S, and GC*2. The sequence shown is that of the GC*2 allele.

Similarity: Belongs to the ALB/AFP/VDB family.

Similarity: Contains 3 albumin domains.

Additional Information

Name Vitamin D Bind.Prot(GC-Glob.)
Related Product Names Vitamin D Bind.Prot(GC-Glob.); DBP; VDB; Group-specific component; Gc-globulin Vitamin D Bind.Prot(GC-Glob.)GC
Intended Use Research Use Only
Purity >95% pure (SDS-PAGE)
Format Purified, Lyophilized. Reconstitute with 242ul distilled water.
Storage Store lyophilized product at -20 C to -70 C. After reconstitution, aliquot and store at -20 C to -70 C. Avoid multiple freeze/thaw cycles.
Molecular Weight 52964
Swiss Prot Number P02774